The common ones
Nausea, reduced appetite, constipation and fatigue are the side effects reported most often, especially in the first few weeks at a new dose step. They tend to fade as the body adjusts, which is the main reason titration schedules exist in the first place.
Timing
Side effects are usually strongest two to four days after a dose, then ease off before the next one. A step increase often brings a smaller repeat of the same pattern.
Less common reports
Some people report heartburn, changes in taste, or hair thinning several months in, usually tied to rapid weight loss rather than the peptide itself. Injection site reactions (redness, a small lump) are also reported and typically clear within a few days.
What tends to help
Smaller meals, eating slowly, and staying upright for a while after eating are the most commonly reported ways people manage nausea. Plenty of water and steady fibre intake are commonly mentioned for constipation.
When to slow down
If a side effect doesn’t ease after a week or two at a given step, many people hold at that dose rather than moving up on schedule. This is a judgement call between a person and their own research, not a one-size instruction, and nothing here should be read as personal medical advice.